Blar i forfatter "Edwin, Bjørn von Gohren"

Viser treff 1-7 av 7

    • A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer 

      Høye, Eirik; Fromm, Bastian; Böttger, Paul H.M.; Domanska, Diana; Kristensen, Annette Torgunrud; Lund-Andersen, Christin; Abrahamsen, Torveig Weum; Fretland, Åsmund Avdem; Dagenborg, Vegar Johansen; Lorenz, Susanne; Edwin, Bjørn von Gohren; Hovig, Eivind; Flatmark, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-14)
      Although microRNAs (miRNAs) contribute to all hallmarks of cancer, miRNA dysregulation in metastasis remains poorly understood. The aim of this work was to reliably identify miRNAs associated with metastatic progression of colorectal cancer (CRC) using novel and previously published nextgeneration sequencing (NGS) datasets generated from 268 samples of primary (pCRC) and metastatic CRC (mCRC; ...

    • Evolution of laparoscopic liver surgery: 20-year experience of a Norwegian high-volume referral center 

      Aghayan, Davit; Kazaryan, Airazat; Fretland, Åsmund Avdem; Røsok, Bård Ingvald; Barkhatov, Leonid; Lassen, Kristoffer; Edwin, Bjørn von Gohren (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-25)
      Background - Laparoscopic liver surgery has evolved to become a standard surgical approach in many specialized centers worldwide. In this study we present the evolution of laparoscopic liver surgery at a single high-volume referral center since its introduction in 1998.<p> <p>Methods - Patients who underwent laparoscopic liver resection (LLR) between August 1998 and December 2018 at the Oslo ...

    • Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: a multicenter propensity score-matched study 

      Sahakyan, Mushegh; Aghayan, Davit; Edwin, Bjørn von Gohren; Alikhanov, Ruslan; Britskaia, Natalia; Brudvik, Kristoffer Watten; D’Hondt, Mathieu; De Meyere, Celine; Efanov, Mikhail; Fretland, Åsmund Avdem; Hoff, Rune; Ismail, Warsan; Ivanecz, Arpad; Kazaryan, Airazat; Lassen, Kristoffer; Magdalenić, Tomislav; Parmentier, Isabelle; Røsok, Bård Ingvald; Villanger, Olaug; Yaqub, Sheraz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-14)
      Background: The role of laparoscopy in the treatment of intrahepatic cholangiocarcinoma (ICC) remains unclear. This multicenter study examined the outcomes of laparoscopic liver resection for ICC.<p> <p>Methods: Patients with ICC who had undergone laparoscopic or open liver resection between 2012 and 2019 at four European expert centers were included in the study. Laparoscopic and open approaches ...

    • Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: amulticenter propensity score-matched study 

      Sahakyan, Mushegh; Aghayan, Davit; Edwin, Bjørn von Gohren; Alikhanov, Ruslan; Britskaia, Natalia; Brudvik, Kristoffer Watten; D’Hondt, Mathieu; De Meyere, Celine; Efanov, Mikhail; Fretland, Åsmund Avdem; Hoff, Rune; Ismail, Warsan; Ivanecz, Arpad; Kazaryan, Airazat M.; Lassen, Kristoffer; Magdalenic, Tomislav; Parmentier, Isabelle; Røsok, Bård Ingvald; Villanger, Olaug; Yakub, Sheraz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-14)
      Background - The role of laparoscopy in the treatment of intrahepatic cholangiocarcinoma (ICC) remains unclear. This multicenter study examined the outcomes of laparoscopic liver resection for ICC.<p> <p>Methods - Patients with ICC who had undergone laparoscopic or open liver resection between 2012 and 2019 at four European expert centers were included in the study. Laparoscopic and open approaches ...

    • Preoperative Inflammatory Markers in Liver Resection for Colorectal Liver Metastases: A National Registry-Based Study 

      Sahakyan, Mushegh; Brudvik, Kristoffer Watten; Angelsen, Jon-Helge; Dille-Amdam, Rachel G.; Sandvik, Oddvar Mathias; Edwin, Bjørn von Gohren; Nymo, Linn Såve; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-04)
      Background Preoperative inflammatory markers were shown to be associated with prognosis following surgery for hepato-pancreato-biliary cancer. Yet little evidence exists about their role in patients with colorectal liver metastases (CRLM). This study aimed to examine the association between selected preoperative inflammatory markers and outcomes of liver resection for CRLM.<p> <p>Methods Data ...

    • The Role of Preoperative Inflammatory Markers in Pancreatectomy: a Norwegian Nationwide Cohort Study 

      Sahakyan, Mushegh; Kleive, Dyre; Dille-Amdam, Rachel G.; Kjeseth, Trond; Waardal, Kim; Edwin, Bjørn von Gohren; Nymo, Linn Såve; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-15)
      Background and purpose Preoperative infammatory markers, such as Glasgow prognostic score, modifed Glasgow prognostic score and C-reactive protein to albumin ratio, were shown to be associated with prognosis in patients undergoing pancreatectomy for cancer. However, little is known about their predictive role in a Western population.<p> <p>Methods The Norwegian National Registry for Gastrointestinal ...

    • T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases 

      Høye, Eirik; Dagenborg, Vegar Johansen; Kristensen, Annette Torgunrud; Lund-Andersen, Christin; Fretland, Åsmund Avdem; Lorenz, Susanne; Edwin, Bjørn von Gohren; Hovig, Eivind; Fromm, Bastian; Inderberg, Else Marit; Greiff, Victor; Ree, Anne Hansen; Flatmark, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-10)
      Background - Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC has been disappointing. Administration of cytotoxic chemotherapy may cause increased density of tumor-infiltrating T cells, which has been associated with improved response to ICI. This study aimed to quantify and ...